Gastroretentive Drug Delivery System for oral Anti Diabet...
Singh, Shailendra / Mishra, Amlan / Sharma, Raghvendra
Most of the oral dosage forms possess several physiological limitations such as variable gastrointestinal transit because of variable gastric emptying leading to non-uniform absorption profiles, incomplete drug release and shorter residence time of the dosage form in the stomach. This leads to incomplete absorption of drugs having absorption window especially in the upper part of the small intestine, as once the drug passes down the absorption...